Raspberry ketones, transdermal fat burners, fat loss, fat burner

So here is a little something i put together that i have been interested in. Raspberry ketones are in two great products Dermatherm from Primordial (we will carry soon) and ThermoGum. Bare with me as there were only a few studies out there on raspberry ketones and its effects on humans.

Raspberry Ketone Overview
Raspberry Ketones significantly increase norepinephrine-induced lipolysis associated with the translocation of hormone-sensitive lipase from the cytosol to lipid droplets in epididymal fat cells. In conclusion, Raspberry Ketone prevents and improves obesity and fatty liver. These effects appear to stem from the action of Raspberry Ketone in altering the lipid metabolism, or more specifically, in increasing norepinephrine-induced lipolysis in white adipocytes [1].

Now if you’re sitting here going what is all that, lets break down the mechanism of Raspberry Ketones a little more in depth.

Norephinephrine
As a stress hormone, norepinephrine affects parts of the brain where attention and responding actions are controlled. Along with epinephrine, norepinephrine also underlies the fight-or-flight response, directly increasing heart rate, triggering the release of glucose from energy stores, and increasing blood flow to skeletal muscle.

Triglycerides are transported through the blood to appropriate tissues (adipose, muscle, etc) by lipoproteins such as chylomicrons. Triglycerides present on the chylomicrons undergo lipolysis by the cellular lipases of target tissues which yield glycerol and free fatty acids. Free fatty acids released into the blood are then available for cellular uptake. Free fatty acids not immediately taken up by cells may bind to albumin for transport to surrounding tissues that require energy [2].

Lipase
Lipase is an enzyme necessary for the absorption and digestion of nutrients in the intestines. This digestive enzyme is responsible for breaking down lipids (fats), in particular triglycerides, which are fatty substances in the body that come from fat in the diet. Once broken down into smaller components, triglycerides are more easily absorbed in the intestines. Lipase is primarily produced in the pancreas, but is also produced in the mouth and stomach. Lipases also act at a specific position on the glycerol backbone of lipid substrate (A1, A2 or A3). For example, human pancreatic lipase (HPL),[3]which is the main enzyme to break down fats in the human digestive system, converts triglyceride substrates found in ingested oil to monoglycerides and free fatty acids.

In Conclusion, Raspberry Ketones trigger a full blown reaction throughout the body. Once ingested by the body, Raspberry Ketones trigger a norepinephrine release. This causes the release of glucose from energy stores and increases the breakdown of triglycerides into free fatty acids. Once this has been completed Lipase takes over and breaks down the fats allowing them to be digested by the intestines. With this taking place your body will need to release more free fatty acids for energy since what was stored is now being burned.